DEPO-PROVERA BRAIN TUMOR LAWSUIT
Were you diagnosed with a brain tumor after receiving Depo-Provera injections for more than one year?
You may be eligible for compensation
- Written By Attorney Troy Bouk
Depo-Provera Lawsuit: Free Case Evaluation
Bouk Law, PLLC is actively reviewing claims on behalf of women nationwide.
Why Are Women Suing Over Depo-Provera?
Depo-Provera (medroxyprogesterone acetate) is a widely used injectable contraceptive medication, administered every three months. A recent study found that using Depo-Provera for more than one year may increase the risk of developing a brain tumor known as meningioma by over five times.
Depo-Provera Lawsuit Info On This Page...
Do You Qualify for a Depo-Provera Lawsuit?
You may be eligible to file a Depo-Provera lawsuit if you:
- Received at least four injections of Depo-Provera or Depo SubQ Provera
- Were later diagnosed with a meningioma tumor
Qualifying Injuries Include:
- The Plaintiff has been diagnosed with one of the following types of meningiomas:
- Meningioma,
- Intracranial meningioma,
- Intercranial meningioma,
- Cranial meningioma,
- Brain meningioma,
- Meninges tumor,
- Arachnoid tumor (but not arachnoid cyst),
- Convexity meningioma,
- Falcine meningioma,
- Parasagittal meningioma,
- Intraventricular meningioma,
- Skull base meningioma,
- Sphenoid wing meningioma,
- Olfactory groove meningioma,
- Posterior fossa/petrous meningioma,
- Suprasellar meningioma,
- Recurrent meningioma,
- Foramen magnum meningioma,
- Meningothelial meningioma,
- Fibrous meningioma,
- Psammomatous meningioma,
- Angiomatous meningioma,
- and/or Secretory meningioma.
Qualifying Products Include:
The Plaintiff was injected with any of the following products containing Medroxyprogesterone Acetate (MPA).
- Depo Provera
- Depo-Provera
- DPCI
- Depo Provera IM
- DMPA
- Depot medroxyprogesterone acetate
- Medroxyprogesterone Acetate
- MPA
- IM MPA
- Depo-SubQ Provera 104
- Greenstone Medroxyprogesterone
- Greenstone MPA
- Prasco Medroxyprogesterone
- and/or Prasco MPA
If you or a loved one developed a meningioma tumor following Depo-Provera use, you may have a valid claim.
Bouk Law is reviewing Depo-Provera injury cases nationwide. You will not pay any fees or costs unless we win your case. Complete the contact form or call us today for a free consultation.
Why File Now?
In February 2025, the Judicial Panel on Multidistrict Litigation (JPML) consolidated all federal Depo-Provera brain tumor lawsuits into a single coordinated proceeding: MDL No. 3140. The litigation is advancing rapidly. If you wait, you may miss critical deadlines. Every day you wait, you risk the statute of limitations on your case expiring which could potentially bar you from ever filing.
Which Federal Court Presides Over MDL No. 3140
The federal court in the Northern District of Florida is handling all Depo-Provera brain tumor lawsuits, combined as MDL No. 3140.
Key Details:
- Presiding Judge: The Hon. Casey Rodgers, known for managing high-profile product liability cases
- Initial Filings: 68 lawsuits centralized at the time of the MDL’s formation
- Purpose: To streamline discovery, promote efficiency, and encourage global settlement negotiations—while protecting the individual legal rights of each plaintiff
The number of cases is expected to grow significantly as more women come forward after learning of the potential link between Depo-Provera and meningioma brain tumors.
What are Meningiomas Symptoms?
Meningiomas may develop slowly, and symptoms may not appear until the tumor has grown large enough to affect surrounding brain tissue. If you’ve received Depo-Provera injections, it’s important to recognize early warning signs.
Common Meningioma Symptoms:
- Vision changes – Blurred vision, double vision, or loss of peripheral vision
- Persistent headaches – Worsening over time, especially in the morning
- Hearing loss or tinnitus – Ringing in the ears or diminished hearing
- Memory issues – Difficulty recalling recent events or general cognitive decline
- Loss of smell – A reduced or total loss of the ability to smell
- Seizures – New or unexplained seizures or convulsions
- Weakness or numbness – Especially on one side of the body
- Speech difficulties – Slurred speech, trouble forming words, or understanding language
- Confusion or disorientation – Mental fog, trouble focusing, or mood changes
- Balance issues – Frequent falls or loss of coordination
If you or a loved one experienced these symptoms and received Depo-Provera, you may be eligible to join the lawsuit to seek compensation.
Call Bouk Law or complete the contact form today for a free confidential case review.
Depo-Provera and Brain Tumor Risk: What does the Science Say?
- A March 2024 study published in The BMJ found that Depo-Provera users were 5.55 times more likely to develop meningiomas than non-users.
- The synthetic hormone in Depo-Provera binds to brain tissue receptors, potentially triggering abnormal tumor growth.
Study Details:
- Population: Over 108,000 women in the French National Health Data System
- Focus: Relationship between progestin-only contraception and brain tumor risk
- Conclusion: A significant and alarming association between Depo-Provera use and meningioma diagnosis
These findings further support legal action against the drug’s manufacturers, who failed to disclose this elevated risk to patients and healthcare providers.
Who Is being Sued?
Current Depo-Provera lawsuits name several pharmaceutical companies as defendants, alleging they failed to properly research the drug’s long-term risks and withheld critical safety information from the public.
Named Defendants:
- Pfizer Inc.
- Pharmacia & Upjohn Co. LLC
- Pharmacia LLC
- Greenstone LLC
- Viatris Inc.
- Prasco, LLC (d/b/a Prasco Laboratories)
These manufacturers are accused of producing and distributing Depo-Provera and its generic equivalents without disclosing the elevated risk of meningioma and other brain tumors associated with prolonged use.
What Compensation Can You Receive?
Women diagnosed with brain tumors after using Depo-Provera may be entitled to significant financial compensation. Each case is evaluated individually based on injury severity, medical needs, and life impact.
Potential damage(s) include:
- Medical expenses – Hospitalization, surgery, medications, rehab, follow-ups
- Future medical needs – Lifelong care, specialist treatment, monitoring
- Lost wages – Missed work during treatment or recovery
- Loss of earning capacity – If the injury limits future employment
- Pain and suffering – Physical discomfort, chronic symptoms
- Emotional distress – Anxiety, PTSD, or depression from diagnosis
- Permanent disability – Cognitive impairment, motor function loss
- Loss of enjoyment of life – Reduced ability to work, socialize, or parent
- Punitive damages – To punish reckless or intentional misconduct
- Out-of-pocket expenses – Travel, assistive devices, home modifications
Wrongful Death Claims:
If a loved one has died due to a brain tumor linked to Depo-Provera, surviving family members may be entitled to:
- Funeral and burial costs
- Loss of financial support
- Loss of companionship and guidance
Don’t Wait to Act
If you believe Depo-Provera caused your brain tumor or serious health complications, you may be entitled to compensation.
Contact Bouk Law, PLLC today for a free, confidential case evaluation. No fees unless we win.
How Much Does a Lawyer Cost?
At Bouk Law, we represent Depo-Provera clients on a contingency fee basis. That means:
- No upfront costs
- No legal fees unless we win your case
What You Get With Our Representation:
- You pay nothing unless we recover compensation for you
- Nationwide support – We review and accept Depo-Provera claims from clients across the United States
- Access to experienced legal advocates – Regardless of your financial situation
We believe every woman harmed by Depo-Provera deserves access to compensation.
How to Get Started – Fast and Free
Step 1: Submit Your Contact Form
Tell us about your Depo-Provera use and diagnosis.
Step 2: Free Case Review
We’ll assess your claim and explain your rights.
Step 3: No Obligation to Proceed
You decide whether to move forward. We’re here when you’re ready.
If you believe Depo-Provera caused your brain tumor or neurological injury, don’t wait.
Why Choose Bouk Law?
✅ We handle mass tort claims nationwide
✅ You speak directly with experienced attorneys
✅ You pay nothing unless we recover compensation
✅ We treat every case with care and urgency
A CLOSER LOOK AT DEPO-PROVERA
Learn how this contraceptive injection works, its medical history, and the risks now linked to brain tumor lawsuits.
Depo-Provera History
Depo-Provera is a hormonal contraceptive injection first approved by the FDA in 1992. It contains medroxyprogesterone acetate, a synthetic form of the hormone progesterone, which works by:
- Suppressing ovulation
- Thickening cervical mucus to prevent sperm from reaching the egg
- Thinning the uterine lining to prevent implantation
The injection is typically administered once every 12 weeks and has been promoted as a convenient, long-lasting birth control option.
With an estimated 70 million women worldwide having used Depo-Provera, the drug’s safety profile has come under renewed scrutiny following studies linking long-term use to increased risk of brain tumors.
If you’ve received multiple Depo-Provera injections and were later diagnosed with a brain tumor, you may be entitled to compensation.
Call Bouk Law, PLLC or complete the contact form for a free, no-obligation consultation today.
How Does Depo-Provera Work?
Depo-Provera is a long-acting hormonal contraceptive that prevents pregnancy through multiple mechanisms. Once injected, the medication delivers medroxyprogesterone acetate, which works by:
- Inhibiting ovulation, preventing the release of an egg from the ovaries
- Thickening cervical mucus, making it harder for sperm to reach the uterus
- Thinning the uterine lining, reducing the likelihood of implantation
- Decreasing sperm penetration and function within the reproductive tract
These combined effects make Depo-Provera one of the most effective injectable contraceptives when administered on schedule.
Common Uses of Depo-Provera
While best known as a birth control method, Depo-Provera is also prescribed for various medical conditions, including:
- Menstrual disorders, such as heavy or irregular bleeding
- Chronic pelvic pain, often associated with endometriosis
- Prevention of ovarian cyst recurrence
- Hormone replacement therapy in certain cases
- Treatment of hirsutism (excessive hair growth)
- Reduction of endometrial cancer risk
- Management of specific hormone-sensitive cancers
Its long-acting formulation made it a popular option for patients seeking convenience and relief from hormone-related symptoms—but the long-term risks are now being questioned.
Understanding Meningioma Brain Tumors
Meningiomas are tumors that develop in the meninges, the protective layers surrounding the brain and spinal cord. While often benign, these tumors can still cause serious health issues depending on their size and location.
Meningioma Classifications:
- Grade I – Slow-growing and typically benign (accounting for roughly 80% of cases)
- Grade II – Atypical tumors that grow faster and may recur
- Grade III – Malignant and aggressive, with a high risk of spreading
Even Grade I meningiomas can lead to vision loss, seizures, and neurological deficits, particularly when located near sensitive brain structures.
How Does Depo-Provera Cause Meningioma Brain Tumors?
Scientific research shows that medroxyprogesterone acetate, the synthetic hormone in Depo-Provera, can bind to progesterone receptors in brain tissue—specifically in the meninges.
This binding is believed to stimulate abnormal cell growth, potentially triggering the formation of meningiomas over time.
The longer Depo-Provera is used, especially beyond one year, the more significant the exposure to this hormonal activity—raising the risk of tumor development.
Depo-Provera Side Effects
While the primary concern in current lawsuits is the risk of brain tumors, Depo-Provera has been linked to a wide range of side effects—some common and temporary, others serious and potentially long-lasting.
Common Side Effects of Depo-Provera:
- Changes in menstrual cycles – Irregular bleeding, heavier or lighter periods, or complete cessation of menstruation
- Weight gain – Gradual or significant increase in body weight
- Headaches – Including worsening of existing migraines
- Mood changes – Depression, mood swings, anxiety, or irritability
- Decreased libido – Lower sexual desire or performance
- Breast tenderness – Pain, swelling, or sensitivity
- Delayed return to fertility – It may take 6 to 18 months after stopping the shot to become pregnant
Less Common but Serious Side Effects:
- Bone density loss – Long-term use may lead to osteoporosis or fractures; the FDA advises limiting use to no more than two years unless absolutely necessary
- Nausea and bloating – Digestive discomfort or distention
- Hair changes – Thinning hair, hair loss (alopecia), or unwanted hair growth (hirsutism)
- Skin reactions – Acne, rashes, or pigmentation changes
- Allergic reactions – Swelling, hives, itching, or breathing difficulties
- Injection site issues – Pain, redness, or swelling where the shot was given
Any woman experiencing persistent or worsening symptoms should consult a healthcare provider promptly. These side effects can be early indicators of larger health risks now being investigated in federal litigation.
Pseudotumor Cerebri Side Effects from Depo-Provera
In rare cases, Depo-Provera has been linked to a serious neurological condition known as pseudotumor cerebri (PTC), or idiopathic intracranial hypertension (IIH).
This condition mimics the symptoms of a brain tumor, even though no tumor is present. It involves increased pressure within the skull, often leading to headaches and vision problems.
Symptoms of Pseudotumor Cerebri:
- Severe, persistent headaches – Often throbbing or pressure-like
- Vision disturbances – Blurred vision, double vision, or temporary vision loss
- Nausea and vomiting – Associated with intracranial pressure buildup
- Tinnitus – Ringing or pulsing sound in the ears, sometimes matching the heartbeat
Treatment Options May Include:
- Medication – Diuretics like acetazolamide to reduce fluid pressure
- Lumbar punctures – Spinal taps to relieve excess cerebrospinal fluid
- Surgical shunt placement – In severe or unresponsive cases
PTC can lead to permanent vision loss if left untreated. Women currently or previously on Depo-Provera who experience these symptoms should seek medical attention immediately.
Experiencing Severe Side Effects from Depo-Provera?
If you were diagnosed with pseudotumor cerebri, meningioma, or another serious condition after using Depo-Provera, you may be eligible for legal compensation.
Contact Bouk Law today to schedule your free case evaluation.
